Research Collected: September 2015

microbiome, hugs, glyphosate, statin-induced myopathy, air pollution, gmo animal feed

The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection

“Some resident bacteria are thought to protect the skin from infection by outcompeting pathogens for resources or by priming the immune system’s response to invaders… We characterized the skin microbiome before, during, and after experimental inoculation of the arm with Haemophilus ducreyi in matched volunteers who subsequently resolved the infection or formed abscesses. Our results suggest that the preinfection microbiomes of pustule formers and resolvers have distinct community structures which change in response to the progression of H. ducreyi infection to abscess formation.

Does Hugging Provide Stress-Buffering Social Support? A Study of Susceptibility to Upper Respiratory Infection and Illness

“Using a sample of 404 healthy adults, we examined the roles of perceived social support and received hugs in buffering against interpersonal stress-induced susceptibility to infectious disease. Perceived support was assessed by questionnaire, and daily interpersonal conflict and receipt of hugs were assessed by telephone interviews on 14 consecutive evenings. Subsequently, participants were exposed to a virus that causes a common cold and were monitored in quarantine to assess infection and illness signs. Perceived support protected against the rise in infection risk associated with increasing frequency of conflict. A similar stress-buffering effect emerged for hugging, which explained 32% of the attenuating effect of support. Among infected participants, greater perceived support and more-frequent hugs each predicted less-severe illness signs.”

Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure

“Our results suggest that chronic exposure to a [Glyphosate-based herbicides (GBH)] in an established laboratory animal toxicity model system at an ultra-low, environmental dose can result in liver and kidney damage with potential significant health implications for animal and human populations.”

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

“In C2C12 myoblasts, several statin lactones reduced respiratory capacity and appeared to be strong inhibitors of mitochondrial complex III (CIII) activity, up to 84% inhibition… These findings could be confirmed in muscle tissue of patients suffering from statin-induced myopathies, in which CIII enzyme activity was reduced by 18%… In conclusion, CIII inhibition was identified as a potential off-target mechanism associated with statin-induced myopathies.”

Ambient Particulate Matter Air Pollution Exposure and Mortality in the NIH-AARP Diet and Health Cohort

“Long-term exposure to PM2.5 air pollution was associated with an increased risk of total and CVD mortality, providing an independent test of the PM2.5 – mortality relationship in a new large U.S. prospective cohort experiencing lower post-2000 PM2.5 exposure levels.”

Genetically modified soybean in a goat diet: Influence on kid performance

“The in vivo and post mortem performance and serum immunoglobulin G (IgG) concentration in kids born from goats fed conventional (group C) or genetically modified (group T) soybean meal were evaluated… Colostrum from the treated groups recorded a significantly (P  < 0.01) lower percentage of protein and fat… Both colostrum and kids serum IgG concentration were significantly (P < 0.01) lower in the treated groups. Transgenic target DNA sequences (35S and CP4 EPSPS) were not detected in colostrum from goats that received a diet containing conventional soybean meal. By contrast, transgenic DNA fragments were amplified (P < 0.05) in samples from goats that received the transgenic soybean.”

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