Suggests that the Nile rat has a similar etiology of Type 2 diabetes mellitus to humans: high carbohydrate diets.
“Dispersing dietary [carbohydrate] by fiber or replacing it by moderate fat (reducing the glycemic index and load) delayed the onset of diabetes but did not prevent signs of insulin resistance. A very low content of dietary [carbohydrate] (high fat) seemed to prevent even these early indicators of insulin resistance.”
45 women in 3 groups: control, continuous exercise (40min per day in 1 session, 5 days per weeks), intermittent exercise (40min per day in 3 sessions, 5 days per week)
“A self-monitoring calorie-restrict diet was recommended to all participants.”
weight loss after 12 weeks:
control: 2.0kg / 4.5lbs
intermittent: 3.3kg / 7.3lbs
continuous: 1.2kg / 2.7lbs
suggests intermittent exercise is more effective than continuous
not addressed:
why did the continuous group lose less weight than the control group?
if 2.0kg / 4.5lbs of weight loss is attributable to calorie restriction, what happened to the weight of those women when removing that restriction?
“we defined 6 latent BMI trajectories: normal weight downward, normal weight upward, overweight stable, overweight obesity, class I obese upward, and class II/III obese upward. Using survival analysis, we found that people in the overweight stable trajectory had the highest survival rate, followed by those in the overweight obesity, normal weight upward, class I obese upward, normal weight downward, and class II/III obese upward trajectories.”
A summary from highest to lowest survival in 9,538 adults aged 51 to 77 years