I came across this set of research articles investigating PCOS and thought it offered insight into the history of the research and some of the important findings. These articles are all freely available.

• 1996 – Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome.
• 1997 – 17 alpha-Hydroxyprogesterone responses to leuprolide and serum androgens in obese women with and without polycystic ovary syndrome offer dietary weight loss.
• 1997 – Lean women with polycystic ovary syndrome respond to insulin reduction with decreases in ovarian P450c17 alpha activity and serum androgens.
• 1998 – Insulin stimulates testosterone biosynthesis by human thecal cells from women with polycystic ovary syndrome by activating its own receptor and using inositolglycan mediators as the signal transduction system.
• 1998 – Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome.
• 1999 – Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome.
• 2001 – Insulin reduction with metformin increases luteal phase serum glycodelin and insulin-like growth factor-binding protein 1 concentrations and enhances uterine vascularity and blood flow in the polycystic ovary syndrome.
• 2002 – Effects of metformin on early pregnancy loss in the polycystic ovary syndrome.
• 2003 – A modern medical quandary: polycystic ovary syndrome, insulin resistance, and oral contraceptive pills.
• 2004 – Metformin therapy increases insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator in women with polycystic ovary syndrome.
• 2004 – Reduced serum glycodelin and insulin-like growth factor-binding protein-1 in women with polycystic ovary syndrome during first trimester of pregnancy.
• 2012 – The link between polycystic ovarian syndrome and type 2 diabetes: preventive and therapeutic approach in Israel.