“The Origins and Drivers of Insulin Resistance”

An article available online from Cell called “The Origins and Drivers of Insulin Resistance” is very technical but well worth a read. The major take-away points are that research supports 3 primary drivers of insulin resistance:

  • inflammation
  • impaired lipid metabolism
  • dysbiosis

… we believe that inflammation, lipid metabolism, and the microbiota are the major interacting components [implicated in insulin resistance] and that other proposed factors ultimately work through one or more of these mechanisms.

Cell – The Origins and Drivers of Insulin Resistance

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