I think high quality methylfolate supplementation may be an important emerging tool. This quote caught my eye and I think it’s worth raising awareness of:

“We have had patients respond to 5-MTHF with such diverse symptoms as chemical sensitivities, irritable bowel syndrome, mental and physical fatigue, autoimmune problems, recurrent infections, and so on.  Patients with mental or emotional problems including depression often show a need for 5-MTHF.  In fact, 5-MTHR is one of the first nutrients we test in any difficult patient, especially those who have seen other doctors with little results.” – Dr. Walter Schmit

http://www.bioticsnw.com/content/methylfolate-plus%E2%84%A2-0